Technology:

RPRx

 

RPRx (Recycling Polycarbonyl Redox Therapy) is a novel therapeutic approach to treatment of health disorders caused by disabled mitochondrial function.

 
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MECHANISM OF ACTION OVERVIEW:

Key Features.

 
 
 

This class of novel proprietary compounds represents a new platform of investigational drug candidates.

 
 

By driving mitochondrial metabolism, RPRx induces a recycling redox mechanism in abnormally proliferating or disabled cells until normal signaling mechanisms are restored.

 
 

This process either leads to metabolism of intracellular debris and prenylated cross-linkages (fixing the diseased cell) or drives diseased cell to apoptosis (programmed cell death).

 
 

Healthy cells have enzymatic mechanisms that prevent over expression of the RPRx mechanism of action.

 
 

Thus, the core mechanism of action selectively targets diseased cells, rather than healthy cells.

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 RESULTS FROM ANECDOTAL ANIMAL STUDIES:

Data.

 

EQUINE MYELOENCEPHALITIS (EPM):

 
 

311

horses treated with intravenous administration of this class of compounds.

296

horses (95%) asymptomatic within 7-14 days.

 
 

EQUINE MELANOMA:

Mode of mechanism suggests apoptosis of neoplastic tissue (without necrosis)

6 of 6

horses completely resolved with no complications

 

JOHNE’S DISEASE - CHRONIC INFLAMMATION:

2 of 2

bulls resolved with no complications.

 
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